Background: Nigeria faces developmental challenges such as food insecurity, limited access to healthcare services, financial exclusion, and high youth unemployment. In contrast, there is a focus on digital adoption and a relatively unexplored area in the socioeconomic impacts of local technologies. The aim is to investigate the potential role of native innovations in promoting sustainable development and enhancing quality of life, as part of ongoing research. Research Methodology: This study employed a sequential mixed-methods approach; primary data were collected and analysed from 1,115 respondents, including surveys of smallholder farmers, household questionnaires, interviews with micro-entrepreneurs, questionnaires for youths, and key informant interviews. Secondary data were supplemented by national statistical and institutional reports. The analytical methods used included difference-in-differences, propensity score matching, multivariate regression, and thematic analysis. Results: Adoption of indigenous NSPRI storage technologies reduced post-harvest loss by 25- 40%. Communities delivered contextually powered service platforms, such as mHealth, fintech performed considerably better than traditional regimes. Fintech added directly to GDP, and its contribution to total output went from 0.7% (2020) to 2.3% (2024). Digital skills training induced a 32% increase in youths‘ employment opportunities but not evenly for both sexes. Lack of infrastructure, fragmented regulation and low digital literacy were key obstacles to adoption. Conclusion: Local technologies have the capacity to uplift the quality of life in Nigeria. But they only work if conditions are right for them. We recommend a number of evidence-based policy recommendations such as the establishment of Technology Innovation Zones, a National Digital Literacy Fund and flexible regulation to create an environment conducive to domestic innovation.