This study examined public-private partnership and public service delivery in Nigeria with particular reference to the Ministries of Health and Works in Delta State. The study was undertaken to determine the extent to which public-private partnership contributes to effective public service delivery, infrastructural development, accountability, efficiency, and improved performance within the public sector. The increasing demand for quality public services amidst inadequate government resources and administrative inefficiency has made public-private partnership an important strategy for enhancing service delivery in Nigeria. The study adopted a survey research design. The population of the study comprised staff of the Ministries of Health and Works in Delta State. A sample size of 377 respondents was selected using simple random sampling techniques. Data for the study were collected through the use of a structured questionnaire designed on a four-point Likert scale. The data collected were analyzed using descriptive statistics such as frequency tables and percentages, while hypotheses were tested using Analysis of Variance (ANOVA). The findings of the study revealed that public-private partnership has significantly improved public service delivery in the Ministries of Health and Works in Delta State. However, the study identified challenges such as corruption, bureaucratic delays, inadequate funding, political interference, and weak policy implementation as major obstacles affecting effective public-private partnership arrangements in Nigeria. Based on the findings, the study concluded that public-private partnership remains an effective mechanism for improving public service delivery in Nigeria. The study therefore recommended that government should strengthen policy frameworks guiding public-private partnership arrangements, ensure transparency and accountability in project implementation, improve monitoring and evaluation systems, encourage private sector participation, and provide adequate funding and institutional support for public-private partnership projects.