The aim of this study was to analyze the variation in the trend of passenger’s vessel accident along waterways in the south-south region. The volume of daily passengers from10 jetties across the coastal states with high volume of inland transportation activities (Rivers, Bayelsa, Delta, Cross River and Akwa Ibom) assessed from the archive of NIWA formed the population of this study. The sample of 395 was determined by applying' the Taro Yamane formula' resulting in the designed, validation and distribution of a total of 395 copies of questionnaire to respondents to obtain relevant information for the study. The data was presented in tables and descriptive statistics used in the discussion while Kruskal Wallis test was employed to analyze the data. The result shows over-speeding (36.4%) and overloading (36.4%) as the main human factors while storm/wind (36.9%) and navigator failure (37.4%) as the leading natural and mechanical factors that causes marine accidents in the area. The calculated value of the Kruskal Wallis test (0.007) indicate that there is no significant variation in the occurrences and frequency of passengers’ vessel accident across different states in the South-South region at p < 0.05. The study revealed that the states have recorded high occurrences of vessel accidents attributable to varied causes in recent times attesting to the fact that there is no improvement in the sector to engender efficiency. Based on the findings, the study recommended periodic conduct of integrity test on vessels, enforcement of regulatory laws, stakeholder’s engagement and collaboration.